Summary: Naive CD4+ T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.Here, we show that TRIB2 is more abundant smartgiro in naive CD4+ than CD8+ T cells and counteracts quiescence exit by suppressing AKT activation.TRIB2 deficiency increases AKT

The giant tabular iceberg A68 broke away from the Larsen C Ice Shelf, Antarctic Peninsula, in July 2017.The evolution of A68 would have been affected by both the Larsen C Ice Shelf, the surrounding sea ice, and the nearby shallow seafloor.In this study, we analyze the initial evolution of iceberg A68A—the largest originating from A68—in

Microorganism culture is highly complex due to the different metabolic pathways, which are very complex.A metabolic phenomenon called overflow is a challenge to overcome in automatic control tasks of microorganism cultures.In this study, a stoneraven d2 nonlinear algorithm by sliding modes (sliding mode nonlinear control, SMNC) is proposed for the

This article reports the numerical study of natural convection in a differentially heated cylindrical annular enclosure with a thin baffle attached to inner wall.The inner and outer walls of the annulus are respectively maintained at higher and lower temperatures, whereas the top and bottom walls are thermally insulated.Using an implicit finite dif

The mechanical responses of dense packings of soft athermal spheres under a finite-rate houston astros sunglasses shear are studied by means of molecular dynamics simulations.We investigate the volume fraction and shear rate dependence of the fluctuations in the shear stress and the interparticle contact number.In particular, we quantify them by de